123: Foundations of Physiology

Introduction to fundamental concepts in physiology and the practice of physiology research through exploration of mathematical models used in physiology research: emphasis on prediction of complex adaptive behavior in health and disease from elementary math, physics, chemistry and biology.

Lecture - Lab Hours: MWF 9:10-10:00 OR MWF 10:20-11:10 OR MWF 11:30-12:20 OR MWF 12:40-1:30, Credit: 3

Course Level: Undergraduate

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223: Design of Experiments for Physiology Research

Team or group formulation and refinement of novel hypotheses and design of controlled in vitro experiments: emphasis on production of publishable research in physiology.

Lecture - Lab Hours: 501: Tues 09:35 AM-12:25 PM (Vivarium III room 120) Thurs 09:35 AM-11:15 PM (VIDI room 109) 502: Tues 02:20 PM-05:10 PM (Vivarium III room 120) Thurs 02:20 PM-04:00 PM (VIDI room 109), Credit: 3(2-1)

Course Level: Undergraduate

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281. Seminar

Exposure to scientists from a variety of biomedical disciplines through attendance at seminars followed by review and discussion of current scientific work in physiology and related subjects, and subsequent student seminar presentations. Prerequisites: Freshman or sophomore classification; approval of instructor.

Credit: 1 to 4

Course Level: Undergraduate

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285. Directed Studies

Course for freshman and sophomore students who desire additional laboratory work in physiology to supplement required courses. Prerequisites: Freshman or sophomore classification; approval of department head.

Credit: 1 to 4

Course Level: Undergraduate

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401. History of Human and Veterinary Medicine in Europe

Addresses the major developments in human and veterinary medicine in Europe from the Middle Ages to the present; explores key events and figures in medical history and analyzes issues of current biomedical concern in an historical context; for example, animal rights, ethics of human experimentation, euthanasia.

Lecture - Lab Hours: (4-0), Credit: 4

Course Level: Undergraduate

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423. Biomedical Physiology I

Physiological principles, review of cellular physiology, and development of an understanding of the nervous system and muscle, cardiovascular, and respiratory physiology; clinical applications related to organ systems.

Lecture - Lab Hours: (3-2), Credit: 4

Course Level: Undergraduate

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424. Biomedical Neuroendrocrinology and Endocrine Disorders

Neuroendocrine (hypothalamus-pituitary) control of puberty, menstruation, ovulation, pregnancy, labor, lactation, female reproductive cycles, male reproductive functions, thyroid and parathyroid, adrenal and kidney, diabetes, obesity, sleep, memory, learning and aging and their endocrine disorders; overview on biosynthesis, transport and signaling of peptide and neuropeptide hormones, steroids and prostaglandins.

Lecture - Lab Hours: (3-0), Credit: 3

Course Level: Undergraduate

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425. Pharmacology.

Introduction to pharmacokinetics and pharmacodynamics; survey of major pharmaceutical classes; uses, mechanisms of action and adverse reactions of selected agents.

Lecture - Lab Hours: (3-0), Credit: 3

Course Level: Undergraduate

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427. Biomedical Physiology II

Continuation of VTPP 423. Fluid balance and acid-base balance; development of an understanding of renal, gastrointestinal, endocrine and reproductive physiology using human and other mammalian models; clinical applications related to organ systems.

Lecture - Lab Hours: (3-0), Credit: 3

Course Level: Undergraduate

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434. Physiology for Bioengineers I

Engineering analysis of living systems; quantitative aspects of physiology and engineering applications to clinical medicine; body fluid balance, solute transport, endocrinology, reproduction physiology, neurophysiology, skeletal and smooth muscle physiology.

Lecture - Lab Hours: Lecture: 3 Lab: 2, Credit: 4

Course Level: Undergraduate

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435. Physiology for Bioengineers II

Engineering analysis of living systems; quantitative aspects of physiology and engineering applications to clinical medicine; vascular physiology, cardiac physiology, bone physiology, regenerative medicine, renal physiology, pathophysiology.

Lecture - Lab Hours: Lecture: 3 Lab: 2, Credit: 4

Course Level: Undergraduate

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438. Analysis of Genomic Signals

Overview of current high throughput technology for data acquisition and analysis of genomic signals (e.g. mRNA or proteins); emphasis on the microarray technology, methods for analyzing microarray data, and approaches to model the underlying phenomena from the systems biology perspective.

Lecture - Lab Hours: (2-2), Credit: 3

Course Level: Undergraduate

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452. Fetal and Embryo Physiology

Introduction to the physiologic processes driving embryonic development and pregnancy; focus on embryo implantation, establishment of the placenta, development of the fetal circulatory systems and the molecular processes governing embryo differentiation and development; special emphasis on the major organ systems affected by pediatric disease and on the actions of teratogens.

Lecture - Lab Hours: (3-0), Credit: 3

Course Level: Undergraduate

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481. Seminar

Exposure to scientists from a variety of biomedical disciplines through attendance at seminars followed by review and discussion of current scientific work in physiology and related subjects, and subsequent student seminar presentations.

Credit: 1 to 4

Course Level: Undergraduate

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485. Directed Studies

Course for junior and senior students who desire additional laboratory work in physiology to supplement required courses.

Lecture - Lab Hours: (0-3), Credit: 1 to 4 each semester

Course Level: Undergraduate

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605. Systemic Veterinary Physiology I

Aspects of cellular physiology, physiology of excitable membranes, physiology of body fluids, neurophysiology, and the physiology of smooth, cardiac and skeletal muscle; provides a basic understanding of mammalian physiology essential as a framework for advanced graduate studies.

Lecture - Lab Hours: (5-0), Credit: 5

Course Level: Graduate

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606. Systemic Veterinary Physiology II

In-depth study covering cardiovascular, respiratory, renal physiology, gastrointestinal and endocrine physiology; provides a basic understanding of mammalian physiology essential as a framework for advanced graduate studies.

Lecture - Lab Hours: (5-0), Credit: 5

Course Level: Graduate

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610. Physiology I

Introduction to physiology: cell physiology, cell signaling, cell cycle, body fluids, translocation of materials, membrane potentials, neurophysiology, autonomic nervous system, thermoregulation, cardiovascular, and muscle physiology.

Lecture - Lab Hours: (5-2), Credit: 6

Course Level: Graduate

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612. Physiology II

Blood and lymph, respiration, renal physiology, and acid-based balance, gastrointestinal physiology, metabolism, endocrinology, and reproduction.

Lecture - Lab Hours: (5-2), Credit: 6

Course Level: Graduate

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623. Biomedical Physiology I

Physiological principles, review of cellular physiology, and development of an understanding of the nervous system and muscle, cardiovascular, and respiratory physiology; clinical applications related to organ systems.

Lecture - Lab Hours: (3-2), Credit: 4

Course Level: Graduate

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625. Pharmacology

Introduction to pharmacokinetics and pharmacodynamics; survey of major pharmaceutical classes; uses, mechanisms of action and adverse reactions of selected agents.

Lecture - Lab Hours: (3-0), Credit: 3

Course Level: Graduate

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627. Biomedical Physiology II

Continuation of VTPP 623 Fluid balance and acid-base balance; development of an understanding of renal, gastrointestinal, endocrine and reproductive physiology using human and other mammalian models; clinical applications related to organ systems.

Lecture - Lab Hours: (3-0), Credit: 3

Course Level: Graduate

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628. Pharmacology I

Pharmacokinetics, pharmacodynamics, CNS pharmacology, autonomic pharmacology, antineoplastic agents, immunopharmacology, recombinant products, fluid and electrolyte therapy, diuretics, pharmacology of the integument.

Lecture - Lab Hours: (4-2), Credit: 5

Course Level: Graduate

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629. Pharmacology II

Antimicrobials, endocrine pharmacology, eicosanoids, anti-inflammatory agents, respiratory pharmacology, anticoagulants and hematinics, GI pharmacology, cardiovascular pharmacology.

Lecture - Lab Hours: (2-2), Credit: 3

Course Level: Graduate

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634. Physiology for Bioengineers I

Cellular anatomy, cellular physiology and biochemistry; systems analysis of digestive, endocrine and musculoskeletal system function including information related to gross anatomy, histology and disease states; quantitative aspects of physiology and engineering applications to clinical medicine.

Lecture - Lab Hours: (3-3), Credit: 4

Course Level: Graduate

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635. Physiology for Bioengineers II

A systems analysis of nervous, cardiovascular, respiratory and urinary function including information related to gross anatomy, histology and disease states; quantitative aspects of physiology and engineering applications to clinical medicine.

Lecture - Lab Hours: (3-3), Credit: 4

Course Level: Graduate

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638. Analysis of Genomic Signals

Overview of current high throughput technology for data acquisition and analysis of genomic signals (e.g., mRNA or proteins); emphasis on microarray technology, methods for analyzing microarray data, and approaches to model the underlying phenomena from the systems biology perspective.

Lecture - Lab Hours: (2-2), Credit: 3

Course Level: Graduate

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651. Epigenetics & Systems Physiology

Journal club format focusing on epigenetic regulation of physiological systems; assignment of papers from primary literature and weekly oral presentations detailing opinions on research; emphasis on fundamental concepts in epigenetics, physiology and the molecular techniques employed to address research hypotheses, discussions of scientific ethics and fraud.

Lecture - Lab Hours: (3-0), Credit: 3

Course Level: Graduate

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652. Fetal and Embryo Physiology

Introduction to the physiologic processes driving embryonic development and pregnancy; focus on embryo implantation, establishment of the placenta, development of the fetal circulatory systems and the molecular processes governing embryo differentiation and development; special emphasis on the major organ systems affected by pediatric disease and on the actions of teratogens.

Lecture - Lab Hours: (3-0), Credit: 3

Course Level: Graduate

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653. Endocrinology

Physiology, biochemistry and pharmacology of the endocrines. Laboratory emphasizes a number of classical experiments with clinical application.

Lecture - Lab Hours: (3-3), Credit: 4

Course Level: Graduate

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655. Vascular Physiology

Structure and function of blood vessels and vascular beds; molecular and cell biology of endothelium and vascular smooth muscle; microcirculation; capillary exchange; regulation of blood flow by local, neural and humoral signals.

Lecture - Lab Hours: (4-0), Credit: 4

Course Level: Graduate

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656. Physiology of the Heart

Structure and function of the heart; molecular and cell biology of cardiac myocytes; electrophysiology of myocardium, pacemaker cells and conducting tissue; cardiac mechanics; control of cardiac performance; coronary circulation.

Lecture - Lab Hours: (4-0), Credit: 4

Course Level: Graduate

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659. Gamete and Embryo Physiology

Physiology of gametes and preimplantation embryos in livestock and laboratory animals; oocyte growth and maturation in-vivo and in-vitro, fertilization in-vivo and in-vitro, embryo transfer, cryopreservation, nuclear transfer, chimera formation, gene transfer.

Lecture - Lab Hours: (2-2), Credit: 3

Course Level: Graduate

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677. Fluorescence Detection: Steady State, Time Resolved and Imaging

Fluorescence spectroscopy and confocal/multiphoton microscopy in research; intro of pharmacology, life science, and physical science students to fluorophores, anisotropy, ligand binding, energy transfer, cytometry, lifetime imaging, correlation spectroscopy, immunocytochemistry, and image analysis with an emphasis on instrumental/sample artifacts, fluorescence application, literature evaluation, and communication of rationales to other scientists.

Lecture - Lab Hours: (4-0), Credit: 4

Course Level: Graduate

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681. Seminar

Review and discussion of current scientific work in physiology and related subjects.

Lecture - Lab Hours: (1-0), Credit: 1

Course Level: Graduate

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690. Theory of Research

Theory and design of research related to current biomedical problems especially those involving study of animal disease; philosophical perspectives underlying historical advances in research pertaining to the study, prevention and treatment of disease.

Lecture - Lab Hours: (3-0), Credit: 3

Course Level: Graduate

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691. Research

Original investigations in veterinary physiology, pharmacology or toxicology to be submitted by writing of thesis or dissertation as partial fulfillment for MS or PhD degree.

Credit: 1 or more each semester

Course Level: Graduate

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910. Physiology I

Introduction to physiology: cell physiology, cell signaling, cell cycle, body fluids, translocation of materials, membrane potentials, neurophysiology, autonomic nervous system, thermoregulation, cardiovascular, and muscle physiology.

Lecture - Lab Hours: (5-2), Credit: 6

Course Level: Professional

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912. Physiology II

Blood and lymph, respiration, renal physiology, and acid-base balance, gastrointestinal physiology, metabolism, endocrinology, and reproduction.

Lecture - Lab Hours: (5-2), Credit: 6

Course Level: Professional

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924. Pharmacology/Toxicology I

Pharmacokinetics, pharmacodynamics, CNS pharmacology, autonomic pharmacology, antineoplastic agents, immunopharmacology, recombinant products, fluid and electrolyte therapy, diuretics, pharmacology of the integument.

Lecture - Lab Hours: (4-2), Credit: 5

Course Level: Professional

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925. Pharmacology/Toxicology II

Antimicrobials, endocrine pharmacology, eicosanoids, antiinflammatory agents, respiratory pharmacology, anticoagulants and hematinics, GI pharmacology, cardiovascular pharmacology.

Lecture - Lab Hours: (2-2), Credit: 3

Course Level: Professional

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