ProfessorPhone: (979) 845-2344Email: [email protected]
Dr. Ken Muneoka is Professor in the Department of Veterinary Physiology and Pharmacology at Texas A&M University. Dr. Muneoka was a faculty member at Tulane University from 1986 to 2014 where he held the John L. and Mary Wright Ebaugh Chair in Science and Engineering. Dr. Muneoka has served as a member of the Army Science Board, a council member for the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and is a fellow in the American Association for the Advancement of Science.
- Cell Biology
Dr. Muneoka’s research is focused on discovering ways to enhance regenerative capabilities of mammalian limbs. His early studies using the amphibian limb as a regeneration model provided the first direct evidence that the process of limb regeneration involved the reutilization of developmental processes. Dr. Muneoka pioneered the study of regenerative capabilities of embryonic mice by developing microsurgical procedures for manipulating mid-gestational stage embryos in utero. Dr. Muneoka’s cumulative work on regeneration in higher vertebrate models has illuminated a road map for tackling the intractable problem of how to induce regenerative responses in mammals. Using the mouse digit tip as a regeneration model, a number of key signaling pathways have been identified as critical for mammalian blastema formation and regeneration, while gain of function studies using non-regenerating digit or limb amputations provide clear examples of how activation of these signaling pathways can induce regenerative responses. Most recently, Dr. Muneoka’s lab has demonstrated that mammalian joints can be induced to regenerate and this has led to in vitro strategies for differentiating articular cartilage that can be used for surgically repair damaged joints.
Ken Muneoka is accepting trainees of these groups:
- Undergraduate Scholars
Conor Dolan: Connor received his undergraduate training in Neuroscience at Tulane University and is now doing his PhD in the laboratory of Dr. Ken Muneoka. His project focuses on understanding the interactions between peripheral nerves and mechanical loading in the context of digit tip regeneration.
Yu-Lieh Lin is now doing his PhD in the laboratory of Dr. Ken Muneoka. His thesis project focuses on investigating the possibility to differentiate mouse adipose stem cells into hyaline cartilage in vitro and determine the repair efficacy of these differentiated cells in articular cartilage defected mice.